The Neuroregenerative Power of Cord Blood
Human Umbilical Cord Blood (hUCB) is a rich, ethically acceptable source of diverse stem cells with unique potential to treat neurodegenerative diseases and injuries.
The Cellular Arsenal of hUCB
Hematopoietic Stem Cells (HSCs)
The most abundant. Can differentiate into microglia and neural lineages (astrocytes/oligodendrocytes) in vitro. High immune tolerance.
Mesenchymal Stem Cells (MSCs)
High proliferative activity. Committed to angiogenesis. Express CD73, CD90, CD105. Differentiate into neurons/glia.
Endothelial Progenitor Cells (EPCs)
Promote potent angiogenesis and neovascularization. Express CD34, VEGF, Tie-2. Crucial for restoring blood flow to injured tissue.
Unrestricted Somatic Stem Cells (USSCs)
Rare but powerful. Can differentiate into ALL three germ layers (ectoderm, mesoderm, endoderm). High proliferation potential.
How hUCB Repairs the Nervous System
hUCB cells exert their therapeutic effects through multiple sophisticated pathways, creating a pro-regenerative environment in the injured brain or spinal cord.
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1
Anti-Inflammatory & Immunomodulation
Reduces infiltration of macrophages/microglia. Decreases pro-inflammatory cytokines (TNF-α) and increases anti-inflammatory IL-10.
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2
Neuroprotection & Anti-Apoptosis
Reduces Fas proteins and caspases (cell death signals). Protects oligodendrocytes and neurons from ischemic death.
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3
Angiogenesis (Blood Vessel Formation)
Secretion of VEGF and GDNF promotes new blood vessel growth, restoring oxygen to damaged tissues.
Therapeutic Targets & Outcomes
Spinal Cord Injury (SCI)
- Improvements in hind limb function (animal models).
- Increased number of regenerating axons.
- Clinical trials show potential for motor score improvement (WISCI).
Stroke (Ischemic)
- Cells migrate to ischemic site and differentiate.
- Reduction in infarct size.
- Protection of white matter integrity via Akt signaling.
Alzheimer's Disease (AD)
- Reduced cerebral Amyloid-beta (Aβ) peptide levels.
- Reduction of CD40+ activated microglia.
- Improvement in spatial memory and exploratory behavior.
ALS (Lou Gehrig's)
- Prolonged survival in SOD1 transgenic mice.
- Reduction in motor neuron death.
- Anti-inflammatory modulation of glia.
The hUCB Clinical Advantage
Compared to other sources of stem cells (such as bone marrow or adipose tissue), Human Umbilical Cord Blood offers superior biological properties for regenerative medicine.
Safety & Purity
- Non-Invasive: Collected without risk to the donor.
- Certified Labs: We exclusively use AATB certified labs with rigorous virus testing.
- No Oncogenicity: These cells are non-tumorigenic and have no risk of forming teratomas.
Immune Privilege
- Immaturity: Neonatal immune system is less developed, reducing rejection risk.
- HLA Tolerance: hUCB cells are more tolerant to HLA mismatches than bone marrow.
- Low GVHD: Significantly lower probability of Graft vs. Host Disease.
Biological Vitality
- Longer Telomeres: Indicates "younger" cells with higher proliferative potential.
- High Potency: Rich in CD34+ and CD105+ markers indicating high regenerative capacity.
- Expansion: Rapid reproduction capacity even in serum-free mediums (USSCs).
Medical Disclaimer
The health and medical information provided on this website is for general educational and informational purposes only.
Not Medical Advice: This information is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or another qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on WHOLE BODY website. No physician-patient relationship is created by this web site or its use.
FDA Statement: Statements and products mentioned on this site have not been evaluated by the Food and Drug Administration (FDA). The information including any discussed therapies or products are not intended to diagnose, treat, cure, or prevent any disease or medical condition.
User Responsibility: You should not use the information on this website for self-diagnosis or to delay seeking professional medical care. Reliance on any information provided by this website is solely at your own risk.
Medical Disclaimer
The health and medical information provided on this website is for general educational and informational purposes only.
Not Medical Advice: This information is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or another qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on WHOLE BODY website. No physician-patient relationship is created by this web site or its use.
FDA Statement: Statements and products mentioned on this site have not been evaluated by the Food and Drug Administration (FDA). The information including any discussed therapies or products are not intended to diagnose, treat, cure, or prevent any disease or medical condition.
User Responsibility: You should not use the information on this website for self-diagnosis or to delay seeking professional medical care. Reliance on any information provided by this website is solely at your own risk.
