Human Umbilical Cord MSCs: A New Era - WHOLE BODY STEM CELL™

The Future is Cord-Derived

Human Umbilical Cord Mesenchymal Stem Cells (HUCMSCs) represent the next evolution in therapy: Painless collection, faster self-renewal, and tri-lineage potency.

Why HUCMSCs Are Superior

Ethical & Non-Tumorigenic

Unlike Embryonic Stem Cells (ESCs), HUCMSCs are harvested from discarded tissue with no ethical concerns and do not form teratomas.

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Superior Proliferation

HUCMSCs have faster self-renewal properties and maintain multipotency for longer periods compared to Bone Marrow MSCs.

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Immuno-Privileged

Low expression of MHC Class II makes them "invisible" to the host immune system, reducing rejection risk.

A Reservoir of Potency

The umbilical cord is not just a vessel; it is a rich reservoir of diverse stem cell populations, including Cord Blood.

  • 1

    Wharton's Jelly

    The gelatinous substance containing a high concentration of primitive MSCs.

  • 2

    Cord Lining

    Source of both Epithelial (CLECs) and Mesenchymal (CLMCs) stem cells for wound healing.

  • 3

    Perivascular Region

    Surrounding the vessels, these cells exhibit robust proliferative capacity.

  • 4

    Umbilical Cord Blood

    Rich in hematopoietic stem cells and UCB-MSCs, used for anticancer research and banking.

The Master Builder: Tri-Lineage Differentiation

HUCMSCs possess the unique ability to differentiate into cells from all three embryonic germ layers, unlocking treatment potential for a vast array of diseases.

🧠 Ectoderm

Neurons & Glial Cells

Capable of differentiating into functional neurons and astrocytes. Used in Stroke and Parkinson's models to restore neuroplasticity.

💪 Mesoderm

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Bone, Cartilage & Fat

Excellent osteogenic and chondrogenic potential. Repair of Cartilage (3x collagen production of BMMSCs) and bone defects.

🫁 Endoderm

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Liver & Islet Cells

Differentiation into hepatocyte-like cells to rescue Liver Fibrosis and insulin-producing cells for Diabetes treatment.

🛡️ The Peacekeeper: Immunomodulation

HUCMSCs actively regulate the immune system, making them ideal for treating autoimmune conditions and preventing rejection.

Inhibits: T-cell, B-cell, and NK cell proliferation.
Secretes: HLA-G5 (soluble isoform) to induce regulatory T cells.
Result: Reduced GVHD and systemic inflammation.

🎯 The Tumor Hunter: Anticancer Effect

HUCMSCs have demonstrated significant ability to attenuate tumor growth in both solid and non-solid cancers.

Mechanisms: Cell-cell contact inhibition, secretion of DKK1 (PTEN pathway), and oxidative stress induction.

Proven Success in Disease Models

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Stroke

Neuroplasticity & functional recovery.

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Diabetes

Alleviates hyperglycemia via islet regeneration.

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Liver Fibrosis

Successful engraftment & fibrosis rescue.

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Corneal Defects

Epithelial repair using Cord Lining cells.

Based on the review article:

Ding, D. C., et al. (2015). Human Umbilical Cord Mesenchymal Stem Cells: A New Era for Stem Cell Therapy. *Cell Transplantation*, 24, 339-347.

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Not Medical Advice: This information is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or another qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on WHOLE BODY website. No physician-patient relationship is created by this web site or its use.

FDA Statement: Statements and products mentioned on this site have not been evaluated by the Food and Drug Administration (FDA). The information including any discussed therapies or products are not intended to diagnose, treat, cure, or prevent any disease or medical condition. 

User Responsibility: You should not use the information on this website for self-diagnosis or to delay seeking professional medical care. Reliance on any information provided by this website is solely at your own risk. 

Address

11050 Crabapple Road

Bldg D, #114

Roswell, GA 30075

Hours

Monday - Friday

9am - 5pm

Contact

+1 (770) 335-7880

[email protected]

Medical Disclaimer

The health and medical information provided on this website is for general educational and informational purposes only. 

Not Medical Advice: This information is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or another qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on WHOLE BODY website. No physician-patient relationship is created by this web site or its use.

FDA Statement: Statements and products mentioned on this site have not been evaluated by the Food and Drug Administration (FDA). The information including any discussed therapies or products are not intended to diagnose, treat, cure, or prevent any disease or medical condition. 

User Responsibility: You should not use the information on this website for self-diagnosis or to delay seeking professional medical care. Reliance on any information provided by this website is solely at your own risk. 

Address

11050 Crabapple Road

Bldg D, #114

Roswell, GA 30075

Contact

+1 (770) 335-7880

[email protected]

Hours

Monday - Friday

9am - 5pm