A Brief History
Ketamine is a safe, fast-acting anesthetic with a variety of applications to treat mental health and chronic pain. It was first synthesized in 1963 as a rapid anesthetic that supported the cardiopulmonary system and had a reduced recovery period, limiting the possibility and severity of adverse side-effects. It was so safe that it became known as a “buddy drug” during the Vietnam War since non-medical personnel could administer it on the battlefield. In 1970, ketamine’s antidepressant properties were discovered, leading to a cascade of positive studies published on its treatment of unipolar depression. Further studies have shown its efficacy for the treatment of PTSD, OCD, Bipolar Depression, Severe Anxiety, Fibromyalgia, Complex Regional Pain Syndrome, and other pain syndromes. Approximately 70% of patients experience a significant reduction in symptoms – many during their first infusion. Now, Ketamine is widely used to heal mood disorders, eliminate suicidal ideations, and alleviate chronic pain.
Do I Qualify? See if Ketamine is Right for YouHow Does It Work?
Ketamine works by increasing synaptogenesis and neuroplasticity, regulating glutamate, decreasing inflammation, and rapidly reversing the effects of stress on the brain.
Increases Synaptogenesis
Synaptogenesis is the formation of new synapses between neurons in the nervous system.
Increases Neuroplasticity
Neuroplasticity is the ability of the brain to form and reorganize synaptic connections, especially in response to new information, new experiences, or following an injury.
Regulates Glutamate
Glutamate is the primary fuel source for the central nervous system.
Decreases Inflammation
Inflammation is part of the body’s immune response, but recent studies show a strong link between inflammation and major depression.
Rapidly Reverses Chronic Stress
Chronic stress shrinks neurons and decreases synaptic connections. The effects of 21 days stress are reversed one day after a single dose of ketamine.
